The Hemophilia and Thrombosis Center of Nevada

2020 W. Palomino Lane Suite 110

Las Vegas, Nevada 89106

702-385-2702

 

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since July 3, 2010

Last updated July 3, 2010

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What Is It??  PROTHROMBIN GENE MUTATION 20210

An abnormality in one of the clotting factors has been identified that results in an increased predisposition to the development of blood clots.

Who Knows If They Have It??

The genetic test confirms the presence of one or two of these genes. This test is reliable while on treatment with Coumadin.

How Do You Get It??

The Factor II 20210a defect is inherited.  Therefore, there is no cure.   The treatment is aimed at preventing the development of blood clots.

What Should You Do About It??

Persons identified at having the 20210a defect are at increased risk of developing blood clots.  If you have this abnormality and have never had a blood clot, you should not be treated with long term blood thinners.  Instead, during times when blood clots are more likely to develop, ie: pregnancy, after surgery, blood thinners may be indicated.  Tobacco usage and hormone supplementation may increase the risk of blood clots developing and therefore should be avoided.

 

 

 

 

 

 

 

 

 

 

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Last modified: May 17, 2010